Sydney Leroux scored two second half goals to lead the Pride to a 5-2 win in Chicago.
Rachel Hill opened the scoring less than two-minutes into the game, and Alex Morgan followed with her 2nd goal of the season.
But Red Stars forward Sam Kerr scored goals in the first and second halves to knot things at 2.
That's when Leroux took things over, helping the Pride bounce back from a tough loss Wednesday to league-leading North Carolina.
Pride star defender Ali Kreiger left the game with a knee injury.