What to know about Lung Nodules
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Pope Leo XIV has been admitted to Rome's Agostino Gemelli University Hospital for a quick procedure to remove a recently discovered, early-stage lung nodule. Dr. Hiren Mehta, Interventional Pulmonologist at UF Health, joined FOX 35's Garrett Wymer live over Zoom to discuss what they are, and how to identify them.

J&J survey says AI may help fight Fla's cancer burden
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A recent Johnson & Johnson survey highlights how AI could help address Florida's heavy cancer burden—projected at 183,100 new cases in 2026—by alleviating rural doctor shortages and reducing late-stage diagnoses. Dr. Lucio Gordan, an oncologist and hematologist from the Florida Cancer Specialists & Research Institute, joined FOX 35'S Garrett Wymer live over Zoom to discuss how this works.

Monday Morning QB: Florida teams face challenges
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Tim Walters, Sports Editor of the Florida Times-Union and FLORIDA TODAY, joined FOX 35's Garrett Wymer live over Zoom for this week's Monday Morning Quarterbacking, where Florida college football and NFL teams saw quite a struggle. 

Christa Pike returns to TN prison after botched execution
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Christa Pike, a woman who survived two doses of lethal injection in Tennessee, is back in prison after her failed execution attempt. Civil Rights Attorney, John Burris, joined FOX 35 News to discuss the legal implications, and what comes next. 

Judge orders White House to stop taxpayer-funded ads
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A federal judge has ordered the Trump administration to stop using taxpayer-funded advertising after lawsuits and criticism from political opponents and legal experts, who argued the ads violated federal law prohibiting public funds from being used for political propaganda. UCF History Professor, Dr. John Sacher, joined FOX 35's Garrett Wymer live over Zoom to discuss this. 

Disney Cruise Line to expand fleet to 13 ships by 2031
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Disney Cruise Line is expanding its fleet to 13 ships by 2031, marked by a major construction milestone for its newest vessel, the Disney Believe, which will feature new onboard offerings and sail its maiden voyage out of Port Everglades. Drew Smith, aka DrewDisneyDude, joined Garrett Wymer live over Zoom to break down the latest. 

How to keep children safe near bodies of water
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Three missing Florida children, ages 3, 5, and 6, were tragically found dead Saturday in separate pond drownings near UCF in Orange County and in Daytona Beach following public alerts. Megan Ferraro, Executive Director of the ZAC Foundation, joined FOX 35's Garrett Wymer live over Zoom to discuss this, and how to keep children safe near bodies of water. 

Hurricane Isaias: NHC update as Cat. 3 heads towards Florida coast
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Jamie Rhome, deputy director of the National Hurricane Center in Miami, shares an update on Hurricane Isaias as it approaches the Florida Panhandle. 

Florida AG warns looters, scammers ahead of Hurricane Isaias
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Florida Attorney General James Uthmeier joined FOX 35's Garrett Wymer to talk about the state's price gouging hotline, and his warning to potential looters or scammers as Hurricane Isaias makes its way towards Florida's northern Gulf coast.

Hurricane Isaias update: Landfall hours away
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Hurricane Isaias is inching closer to the Florida Panhandle, where its expected to make landfall as a strong Category 3 hurricane. FOX 35's Laurel Blanchard goes over the latest forecast, impacts, tornado threats, and landfall projections.

Tampa Bay Rays hot streak rolls into the ALCS
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Alex Murphy, Co-Founder of the Rays the Roof Podcast joins FOX 35's Garrett Wymer live via Zoom to preview the Tampa Bay Rays' time in the American League Championship Series, where they'll face one of the Chicago White Sox or Cleveland Guardians with home-field advantage on a potential World Series run.

Iran Latest: Trump rules out Iran strikes before midterms
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President Donald Trump stated that the U.S. will hold off on further military strikes against Iran until after the November 3 midterm elections, following intense backlash over previous comments about the war in the Middle East.  Dr. Houman Sadri, Education Director with the Information and Policy Analysis Center, joined FOX 35's Garrett Wymer live over Zoom to break down the latest. 

Community Crossroads: Indoor things to do in Orlando
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Ashley Edwards and Sarah Barkley joined FOX 35's Garrett Wymer live over Zoom to discuss the best indoor events this weekend. 

Orlando City to play Columbus at Inter & Co.
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Coming off 4 straight losses, Orlando City Lions are set to play Columbus Crew, with Starboy Justin Ellis potentially taking the pitch. Neil Sika, MLS Analyst and commentator, joined FOX 35's Garrett Wymer live over Zoom to break down what to expect to see. 

Silverstein brings My Heroine to Warped Tour Orlando
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Shane Told, Lead Vocalist for Silverstein joins FOX 35's Garrett Wymer live via Zoom ahead of the band's appearance at Warped Tour Orlando at Camping World Stadium in November, plus a history lesson Shane's scream voice, forming the band and playing shows in Florida as one of the pillars of the scene for the last 25 years.

Can gene therapy restore basic sight in blind patients?
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New research conducted by the New England Journal of Medicine reports that an experimental optogenetic treatment has helped some patients with advanced retinitis pigmentosa detect and locate objects. Dr. José-Alain Sahel, Distinguished Professor and Chairman of the Department of Ophthalmology at the University of Pittsburgh, led the research on this study. He joined FOX 35's Garrett Wymer live over Zoom. 

Seminole Tribe files lawsuit against DraftKings
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The Seminole Tribe of Florida has sued DraftKings, saying that the group is running an illegal sports betting ring in the Sunshine State. Dr. Adrien Bouchet, Director of UCF's DeVos Sports Management Program, joined FOX 35's Garrett Wymer live over Zoom to break down what this means. 

Crew-12 splashes down successfully, Hurricane Isaias latest
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After 235 days aboard the International Space Station, SpaceX Crew‑12 splashed down off the Southern California coast at about 11:35 a.m. ET Thursday morning. Ken Kremer, Managing Editor of Space UpClose, joined FOX 35's Jack Royer live over Zoom to discuss the latest. 

Tropics forecast: Hurricane Isaias, flood warnings
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Evacuation orders have been issued for several Florida counties after Tropical Storm Isaias was upgraded into a Hurricane. FOX 35 Storm Team Meteorologist Laurel Blanchard broke down the latest in the tropics. 

Paramount completes Warner Bros. acquisition
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Dr. Nicole Richter, Associate Professor and Director of Film Studies at Rollins College, joined FOX 35's Garrett Wymer live over Zoom to examine how the acquisition of Warnor Bros. Discovery by Paramount will shape the entertainment landscape.