Goran Dragic added 22 points as Miami won for the third time in four games, including a 94-88 overtime victory against New Orleans on Christmas. Gerald Green scored 15 points, and Bosh also had 10 rebounds.
Orlando led 76-69 after three, but Wade fueled Miami's rally with 12 points in the fourth. The Heat outscored the Magic 39-25 in the final period.
Nik Vucevic led Orlando with 22 points and 10 rebounds. Elfrid Payton added 16 points and seven assists.