Firefighters said the accident happened around 5 a.m. Sunday at Indigo Crossing Drive and Manitoba Way in Viera.
The driver hit the home and was trapped inside the car. Officials said after they cut the driver out, they were airlifted to Holmes Regional Medical Center.
No one inside the home was injured and the Brevard County Building Department will be coming to the home to assess the damage before they can remove the car, officials said.
The Florida Highway Patrol is investigating the cause of the accident.