At around 10:30 Friday night, Seminole County deputies responded to a robbery call on the Red Bug Lake Road pedestrian overpass.
Deputies found a man stabbed on the bridge.
He was transported to the hospital in stable condition.
Deputies found a trail of blood leading away from the scene which prompted a check of local hospitals.
Two 17-year-olds had just arrived at a nearby emergency room - one of them covered in blood.
A witness identified them as the two involved in the stabbing and both were arrested.
Investigators determined the incident was the result of a drug deal gone wrong.