Firefighters said the crash happened sometime Saturday night, but the 911 call came in at 8:43 a.m., Sunday.
The crash happened in the 21000 block of SE 127th Street Road in Umatilla. The Ford Expedition was found rolled over, officials said.
Firefighters said when they found the car, they found that all five people inside had been ejected. at 40-year-old man, a 40-year-old woman and a 14-year-old girl were killed.
A 16-year-old and 14-year-old, both girls, were taken to the hospital and were listed in critical condition.
The Florida Highway Patrol is investigating the cause of the crash.